Authors

 

Milica Gleđa¹, Petar Vuleković^1,2, Đula Đilvesi^1,2, Nenad Krajčinović², Igor Horvat², Bojan Jelača^1,2, Jagoš Golubović^1,2, Nada Vučković^1,3, Tanja Lakić^1,3, Filip Pajičić^1,2, Nebojša Lasica^1,2, Marko Despotović², Dušan Rodić<sup>2

1</sup>Faculty of Medicine, University of Novi Sad, Novi Sad
²Clinic of Neurosurgery, University Clinical Centre of Vojvodina, Novi Sad Serbia
³Centre for Pathology and Histology, University Clinical Centre of Vojvodina, Novi Sad Serbia

 

UDK: 616.831-002

The paper was received / Rad primljen: 26.09.2022.

Accepted / Rad prihvaćen: 30.09.2022.

 

Correspondence to:

Milica Gleđa
Medicinski fakultet, Novi Sad
Hajduk Veljkova 3
21000 Novi Sad
Tel: 065 410-35-78
e-mail: milica.gledja@gmail.com

 

 

Abstract

 

 

Brain abscesses are life-threatening infections that still present serious clinical challenge despite advancements in diagnostic and therapeutic techniques. Streptococci are group of bacteria most commonly cultured from immunocompetent patients with bacterial brain abscess, especially the Streptococcus anginosus/milleri group. These bacteria normally reside in the oral cavity, intestines and female genital tract and they have a proclivity for abscess formation. Abscesses are usually presented as single lesions most often located in frontal and temporal lobes that are seen on CT examination of the head as lesions with ring enhancement after intravenous administration of contrast, surrounded by zone of edema. Here, authors present a case of an immunocompetent 24-year-old male who developed a S. constellatus brain abscess. The patient was treated with a combination of surgical resection and antimicrobial therapy with good outcome.

 

 

 

Key words:

Brain abscess; Streptococcus constelatus; Immunocompetent; Case report

 

 

 

Sažetak

Apscesi mozga su životno ugrožavajuća stanja koja i dalje predstavljaju značajan klinički problem uprkos novim otkrićima u medicini kako u dijagnostici, tako i samim terapijskim metodama. Smatra se da su najčešći uzročnici apscesa mozga kod imunokompetentnih pacijenata bakterije iz grupe Streptokoka i to najčešće Streptococcus anginosus/milleri grupa. Ove bakterije predstavljaju saprofitnu floru usne duplje, gastrointestinalnog trakta i ženskih genitalnih organa i imaju afinitet ka formiranju apscesa. Ove lezije su najčešće samostalne, iako mogu biti i multiple, i najčešće se nalaze u frontalnom, a zatim u temporalnom režnju mozga. Na CT pregledu glave se prikazuju kao multiple ili jedinstvene lezije čija ivica (tačnije kapsula) povećava svoj denzitet nakon primene intravenskog kontrasta, okružena zonom hipodenziteta koja odgovara okolnom edemu mozga. U ovom radu, autori prikazuju slučaj imunokompetentnog, mladog, dvadesetčetvorogodišnjeg bolesnika kod kog je otkriven streptokokni apsces mozga. Bolesnik je lečen kombinacijom hirurškog lečenja i primenom antibiotske terapije sa dobrim krajnjim ishodom.

 

 

Ključne reči:

Apsces mozga; Streptococcus constelatus; Imunokompetentni; Prikaz slučaja.

 

 

 

 

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PDFGleđa M. et al MD-Medical Data 2022;14(1-2): 051-053