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ASSESSMENT OF NONINVASIVE VENTILATION (NIV)EFFECTIVENESS IN THE COVID19 INFECTION: A CLINICAL REVIEW /

PROCENA EFIKASNOSTI NEINVAZIVNE VENTILACIJE (NIV) U COVID19 INFEKCIJE: KLINIČKI PREGLED

Authors

 

Biljana Lazović1, Radmila Dmitrović1, Isidora Simonović1, Antonio M. Esquinas1,2

1Department of Pulmonology, University Clinical Center „Zemun” e-mail: lazovic.biljana@gmail.com; radadmitrovic94@gmail.com;
1 Intensive Care Unit, Hospital Morales Meseguer, Murcia, Spain; e-mail: antmesquinas@gmail.com

 

UDK: 616.98:578.834
615.816


The paper was received / Rad primljen: 11.09.2021.

Accepted / Rad prihvaćen: 30.10.2021.

 


Correspondence to:


Biljana Lazović
University Clinical Center „Zemun“
Belgrade, Serbia
Vukova 9, Zemun, 11080 Belgrade
Self-phone: +381 62212040
e-mail: lazovic.biljana@gmail.com

 

 

Abstract

 

Introduction: Noninvasive ventilation (NIV) refers to the administration of ventilatory support without using an invasive artificial airway, endotracheal, or tracheostomy tubeThe use of NIV worldwide is on the rise, and the number of indications increases every day, especially its use in SARS-CoV2 infection where thereis still uncertainty about its effectiveness. Materials and methods: We searched three electronic databases: PubMed, Embase, and Cochrane Library withthe following keywords: “NIV and COVID19” OR“SARS-CoV-2 and NIV” OR “NIV failure in COVID19 ”, and “NIV in respiratory failure during COVID19”. We found 56 papers of which 21 were included in the study. In the table, we present significant data from retrospective, observational and cross-sectional studies related to the application of NIV in COVID19, the countries where the studies were conducted, the median age of respondents, the number of respondents on NIV, and its failure. Conclusion:According to available data, the NIV failure ranges between 10,93% to 74% depending on the number of respondents who were included in the research. NIV continues to be the method of choice in the treatment of COVID19 patients but its efficacy should be examined through more studies.

 

Keywords:

COVID19, noninvasive ventilation, failure, epidemiology

 

 

 

Sažetak

 

Uvod: Neinvazivna ventilacija (NIV) predstavlja primenu ventilatorne podrške bez upotrebe invazivnih, arteficijalnih disajnih puteva, endotrahealne kanile ili traheostome. Upotreba NIV-a širom sveta je u porastu a broj indikacija se povećava svakim danom, posebno je značajna njegova primena kod SARS-CoV2 infekcije gde još uvek postoji nedoumica u pogledu njegove efikasnosti. Materijal i metode: Pretražili smo tri elektronske baze: PubMed, Embase iCochrane Librarysa sledećim ključnim rečima: “NIV i COVID19” ili “SARS-CoV2 i NIV” ili “neuspeh NIV-a u COVID19” i “NIV u respiratornoj insuficijenciji tokom COVID19”. Pretražili smo 56 radova od kojih je 21 uključen u studiju. Tabelarno smo prikazali podatke iz retrospektivnih, opservacionih i studija preseka vezanih za primenu NIV-a u COVID19 infekciji, zemlje u kojima su studije sprovedene, prosečnu starost ispitanika, broj ispitanika kod kojih se primenjivao NIV i njegov neuspeh u primeni. Zaključak: Prema dostupnim podacima neuspeh u primeni NIV-a kreće se između 10,93% i 74% u zavisnosti od broja ispitanika koji su bili uključeni u istraživanja. NIV je i dalje metod izbora u lečenju pacijenata sa COVID19 infekcijom ali njegovu efikasnost treba ispitati kroz više studija.


Ključne reči:

COVI19, neinvazivna ventilacija, neuspeh, epidemilologija

 

 

 

 

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PDF: 13-MD-Vol 13 No 3-4 Sept-Dec 2021_Lazović B. et al.pdf

 

 

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