md-medicaldata

Authors

 

Mersudin Mulić¹, Biljana Lazović², Radmila Dmitrović², Sanja Šarac³, Rade Milić³, Vladimir Zugić <sup>4

1</sup>State University Novi Pazar, Serbia
²University clinical center "Zemun", Belgrade, Serbia
³Military Medical Academy, Clinic for pulmonology, Belgrade
⁴Clinic for lung diseases, Clinical center of Serbia, Belgrade, Serbia, University of Belgrade, Serbia

 

UDK: 613.7:612.217

The paper was received / Rad primljen: 20.02.2020.

Accepted / Rad prihvaćen: 28.02.2020.

 

Correspondence to:

Biljana Lazović
University Clinical Center "Zemun", Belgrade, Serbia
Vukova 9, Zemun, 11080 Belgrade
cell phone +381 62212040

 

 

Abstract

 

Introduction: The  simplified concept of respiratory urge is to consider it as the integrated "exit" from the CNS to the respiratory muscles of the "pump". This urge is a result of a complex central respiratory sample generation, and may occur  in abnormal situations, e.g. of pathological or pharmacological origin, be altered. The ventilatory drive is affected by some factors such as chemosensitivity, basal arterial oxygen or carbon dioxide tension, mechanical impedence and breathing muscle dysfunction. Dulled ventilatory urge or a decrease in the perception of dyspnea in certain conditions could lead to a reduce in the alarm reaction to dangerous situations such as severe airway obstruction, severe hypoxemia, or severe hypercapnia. Aim: The purpose of this systematic review is to obtain differences in respiratory drive among untrained and trained subject.  We have searched Pubmed database and the key words were: respiratory drive. We have thoroughly studied 46 articles. Conclusion: Physical activity plays crucial part in respiratory adaptation, improving respiratory drive which could lead to better and faster response on stronger effort, without fatigue in untrained subjects. To reach respiratory adapatation to stonger stimuli, physical activity must be continuous and intense.

 

 

Key words:

ventilation, trained subjects, CO2, chemoreceptors, exercise

 

 

Sažetak

 

Uvod: Ventilatorni nagon se pojednostavljeno može prikazati kao integrisani, izlazni odgovor centralnog nervnog sistema ka respiratornoj muskulaturi. Ventilatorni nagon predstavlja rezultat kompleksnog generisanja obrazaca respiratornog centra, pri čemu oni mogu biti izmenjeni pod dejstvom patoloških ili farmakoloških faktora .Ovaj sistem je pod direktnim uticajem hemoreceptora, parcijalnog pritiska kiseonika i ugljen dioksida, i zavisi od otpora i eventualne disfunkcije respiratorne muskulature. Njegovo zatajenje ili redukcija percepcije dispnee u okviru pojedinih stanja može voditi neadekvatnoj reakciji na ugrožavajuće situacije poput ozbiljne opstrukcije disajnog puta, teške hipoksemije odnosno hiperkapnije. Cilj: Svrha ovog pregleda je da se dobiju podaci o razlikama respiratornog nagona kod neutreniranih i utreniranih osoba. Pretražili smo Pubmed bazu sa „respiratorni drajv“ kao ključnom reči i detaljno smo proučili 46 članaka. Zaključak: Fizička aktivnost igra značajnu ulogu u respiratornoj adaptaciji. Kao intenzivna i kontinuirana, fizička aktivnost unapređuje ventilatorni nagon i čini odgovor neutreniranih osoba bržim i boljim na teži fizički napor, bez osećaja umora.  Da bi se postigla respiratorna adaptacija na jače podražaje, fizička aktivnost mora biti kontinuirana i intenzivna.

 

 

Ključne reči:

ventilacija, utrenirane osobe, CO2, hemoreceptori,vežbanje.

 

 

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PDF Mulić M. et al • MD-Medical Data 2020;12(1): 011-014