md-medicaldata

Authors

 

Ivana I. Kavečan^1,2, Jadranka Jovanović Privrodski^1,2, Milan R. Obrenović², Kolarski Milenko², Krasimira Kalinova³, Boris K. Privrodski⁴, Đerđi Erdeš Kavečan⁵, Savić N Radojica<sup>1,2

1</sup> University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia
² Pediatric Clinic, Institute for Children and Youth Health Care of Vojvodina, Novi Sad, Serbia
³ Pediatric Surgery; Trakia University; Faculty of Medicine; Stara Zagora, Bulgaria
⁴ Pediatric Surgery Clinic, Institute for Children and Youth Health Care of Vojvodina, Novi Sad, Serbia
⁵ Državni Univerzitet u Novom Pazaru, Departmant za Filozofske nauke, Studijska grupa Psihologija, Novi Pazar, Serbia

 

UDK: 618.177:575

The paper recieved / Rad primljen: 20.04.2018.

Accepted / Rad prihvaćen: 11.05.2018.

 

Corresponding to:

Prof. dr Ivana Kavečan
Faculty of Medicine, University of Novi Sad
Hajduk Veljkova 3
21000 Novi Sad, Srbija
tel. 021 4880444
e-mail: ivana.kavecan@mf.uns.ac.rs

 

 

Abstract

 

The female fertility is the highest in the life span between 20-30 years of age. Healthy women in the age of the greatest fertility have 20-25% chance of getting pregnant in every monthly cycle. Genetic factors significantly affect reproduction. Possible genetic causes of infertility in women are: congenital anomalies, chromosomal anomalies, gene mutations, and gene polymorphism. In order to provide adequate genetic information to spouses, a significant detection of genetic factors of female infertility prior biomedically assisted fertilization is significant.

 

 

Key words:

Infertility, Female; Chromosome Aberrations; Karyotyping; Mutations; Polymorphisms

 

 

Sažetak

 

Ferilitet žene je najveći u životnoj dobi između 20 - 30. godine života. Zdrave ženske osobe u dobi najveće fertilnosti imaju 20-25% šansi da ostvare trudnoću u svakom mesečnom ciklusu. Genetski faktori značajno utiču na reprodukciju. Mogući genetski uzroci infertiliteta kod žena su: kongenitalne anomalije, hromozomske anomalije, mutacije gena i polimorfizam gena. Kako bi se mogla pružiti adekvatna genetska informacija supružnicima, značajna je detekcija genetskih faktora ženskog infertiliteta pre samog postupka biomedicinski potpomognute oplodnje.

 

 

Ključne reči:

ženski infertilitet; kariotipizacija; hromozomske aberacije; mutacije; polimorfizam

 

 

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