Go to content

Main menu:








CIP -  Каталогизација у публикацији
Народна библиотека Србије, Београд
MD : Medical Data : medicinska revija = medical review / glavni i odgovorni urednik Dušan Lalošević. - Vol. 1, no. 1 (2009)- . - Zemun : Udruženje za kulturu povezivanja Most Art Jugoslavija ; Novi Sad : Pasterovo društvo, 2009- (Beograd : Scripta Internacional). - 30 cm

Dostupno i na: - Tri puta godišnje.

ISSN 1821-1585 = MD. Medical Data
COBISS.SR-ID 158558988




Jemal Wakushie, Fekede Bekele Daba
School of Pharmacy, College of Health Sciences, Jimma University, Ethiopia.


• The paper was received on 26.08.2016. / Accepted on 08.09.2016.


Correspondence to:
Fekede Bekele Daba(B.Pharm, M.Pharm, R.Ph)
School of Pharmacy, College of Health Sciences, Jimma University, Ethiopia.
P.O.Box: 378
Mobile: +251-935970999




Background: Poisoning, whether accidental or intentional, is a significant global public health problem. Studies on the causes and consequences of acute poisonings are scarce in Ethiopia. Thus, the aim of this study was to assess the circumstances of acute poisoning and determine the types of management and its outcome in Adama Referral Hospital, Ethiopia.
Methods: A cross-sectional study design involving retrospective chart review of acute poisoning adult cases presented to the hospital from February 2013 to January 2015 was conducted using structured format. SPSS software version 20.0 was used for data entry and analysis. Chi-square statistic (χ²) was calculated to determine the relationship between the variables at 95% CI and p-value ≤ 0.05 was used to determine significance.
Result: The study included 226 patients, of which about 53% were females. Mean age was 25.18±9.55 years and majority was below 35 years of age (86.3%). Most cases (81.9%)were intentional poisoning. Poisonous agents associated with most cases were household cleansing agents (41.6%), followed by organophosphates and drugs. The overall mortality rate was 7.5%and the majority was observed in males (64.7%).
Conclusion: Acute poisoning is common and an important clinical emergency, highlighting the importance of early diagnosis, treatment and prevention. Limiting the availability of, and access to, highly toxic chemicals can help reduce the number of intentional poisoning cases in addition to educational programs that emphasis on preventive measures among the general public.



Key words

poisoning; household; cleansing agents;Adama Referral Hospital, Ethiopia





  1. Pokhrel D, Pant S, Pradhan A, Mansoor S. A comparative retrospective study of poisoning cases in central, zonal and district hospitals. Kathmandu University journal of science, engineering and technology. 2008; 4(1):40-8.
  2. Konradsen F, van der Hoek W, Cole DC, Hutchinson G, Daisley H, Singh S, Eddleston M. Reducing acute poisoning in developing countries—options for restricting the availability of pesticides. Toxicology. 2003; 192(2):249-61.
  3. WHO. International Program on Chemical Safety (IPCS) Poisoning Prevention and Management, 2010. Available at: (access date: 18.05.2016).
  4. Nhachi CF, Kasilo OM. Household chemicals poisoning admissions in Zimbabwe's main urban centres. Hum ExpToxicol. 1994; 13(2):69-72.
  5. Wesseling C, McConnell R, Partanen T, Hogstedt C. Agricultural pesticide use in developing countries: health effects and research needs. International Journal of Health Services. 1997; 27(2):273-308.
  6. Roberts DM, Aaron CK. Managing acute organophosphorus pesticide poisoning. BMJ 2007; 334:629.
  7. Desalew M, Aklilu A, Amanuel A, Addisu M, Ethiopia T. Pattern of acute adult poisoning at Tikur Anbessa specialized teaching hospital, a retrospective study, Ethiopia. Hum ExpToxicol. 2011; 30(7):523-7.
  8. Sawalha AF, Sweileh WM, Tufaha MT, Al‐Jabi DY. Analysis of the pattern of acute poisoning in patients admitted to a governmental hospital in Palestine. Basic & clinical pharmacology & toxicology. 2010; 107(5):914-8.
  9. Harriss L, Hawton K. Deliberate self-harm in rural and urban regions: a comparative study of prevalence and patient characteristics. SocSci Med. 2011; 73(2):274-81.
  10. Shadnia S, Esmaily H, Sasanian G, Pajoumand A, Hassanian-Moghaddam H, Abdollahi M. Pattern of acute poisoning in Tehran-Iran in 2003. Hum ExpToxicol. 2007; 26(9):753-6.
  11. Akhlaghi M, Arbabi Z, Khadivi R. Pattern of acute poisoning in Shahrekord (Western Iran). Asian Journal of Epidemiology. 2009; 2(1):9-12.
  12. Tüfekçi IB, Curgunlu A, Şirin F. Characteristics of acute adult poisoning cases admitted to a university hospital in Istanbul. Hum ExpToxicol. 2004; 23(7):347-51.
  13. Patil A, Peddawad R, Verma VC, Gandhi H. Profile of acute poisoning cases treated in a tertiary care hospital: a Study in Navi Mumbai. Asia Pacific Journal of Medical Toxicology. 2014; 3(1):36-40.
  14. Z’gambo J, Siulapwa Y, Michelo C. Pattern of acute poisoning at two urban referral hospitals in Lusaka, Zambia. BMC Emergency Medicine 2016; 16:2
  15. Singh B, Unnikrishnan B. A profile of acute poisoning at Mangalore (South India). J Clin Forensic Med. 2006; 13(3):112-6.
  16. Camidge DR, Wood RJ, Bateman DN. The epidemiology of self‐poisoning in the UK. British journal of clinical pharmacology. 2003; 56(6):613-9.

UDK: 616-099-083.9(63)
COBISS.SR-ID 226166284

PDF Wakushie J. and Fekede Bekele D. • MD-Medical Data 2016;8(3): 185-189

Naslovna | Revija | Galerija | Dešavanja | Instrukcije | Redakcija | Izdavač | Prijatelji sajta | Saradnja | Kontakt | Site Map

Back to content | Back to main menu