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ADHERENCE TO PHARMACOTHERAPY IN PATIENTS WITH OSTEOPOROSIS – a brief review /

PRIDRŽAVANJE TERAPIJE KOD PACIJENATA SA OSTEOPOROZOM – kratak pregled

Authors

 

Ivana Minaković1,2, Jelena Zvekić-Svorcan1,3, Sandro Kopilović4,5

1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia
2Health Center Novi Sad, Novi Sad, Serbia
3Special Hospital for Rheumatic Diseases, Novi Sad, Serbia
4Institute for Emergency Medicine, Novi Sad, Serbia
5Department of Scientific Research Education and International Cooperation, Novi Sad, Serbia

 

UDK: 616.71-007.233-085


The paper was received / Rad primljen: 18.02.2021.

Accepted / Rad prihvaćen: 28.02.2021.

 


Correspondence to:


Ivana Minaković,
University of Novi Sad, Faculty of Medicine,
Hajduk Veljkova 3, 21000 Novi Sad, Serbia,
e-mail: ivana.minakovic@uns.ac.rs

 

 

Abstract

 

Osteoporotic fractures are a significant cause of morbidity and mortality, and their annual prevalence is expected to increase due to population ageing and increased lifespan. Although the incidence of osteoporotic fractures can be reduced by 30-70% with regular use of pharmacotherapy, more than half of patients do not start therapy or do not use it appropriately. Medication non-adherence may be associated with worsening of disease symptoms, complications, increase in the frequency of hospitalizations and mortality. The results of various studies suggest an association between non-adherence in patients with osteoporosis and more complicated medication regimes, the severity of symptoms, personal perception of risk and benefits, patient knowledge and education, age, polypharmacy, side effects. It is important to identify risk factors associated with non-adherence and to achieveefficient communication between the patient and the healthcare providers to improve adherence and thus the outcome of the disease.

 

 

 

Keywords:

Anti-osteoporotic therapy; Adherence;  Osteoporosis; Predictors ofnon-adherence

 

 

 

Sažetak


Osteoporotski prelomi su značajan uzrok morbiditeta i mortaliteta, a očekuje se da će godišnja prevalenca ovakvih preloma rasti zbog starenja stanovništva i produženog životnog veka. Iako se redovnimkorišćenjem farmakoterapije učestalost osteoporotski preloma može smanjti za 30-70%, više od polovine pacijenata ne započinje da koristi terapiju, ili je ne koristi na odgovarajući način.Neadherenca terapiji može biti povezana sa simptomatskim pogoršanjem bolesti, komplikacijama, povećanjem učestalosti hospitalizacije i mortaliteta. Rezultati različitih studija ističu povezanost između neadherence terapiji i složenijih režima korišćenja lekova, težine simptoma, lične percepcije rizika i koristi, znanja i obrazovanja pacijenta, starosti, polifarmacije, neželjenih efekata. Važno je identifikovati faktore rizika povezane sa neadherencom i postići efikasnu komunikaciju između pacijenata i zdravstvenih radnika kako bi se poboljšala adherenca, a tako i ishod bolesti.


Ključne reči:

Antiosteoporotska terapija; Adherenca; Osteoporoza; Prediktori neadherence;

 

 

 

 

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PDF 01-MD-Vol 13 No 1 2021_Minakovic et al

 

 

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