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EOSINOPHILIC CYSTITIS IN A PATIENT WITH HEMATURIA: A RARE CASE REPORT /

EOZINOFILNI CISTITIS KOD PACIJENTA SA HEMATURIJOM: PRIKAZ RETKOG SLUČAJA

Authors

 

Ivo Vujichikj1 and Mihail Penev1

1University Clinic for Urology,University Clinical Centre “Mother Theresa”, Skopje, Republic of North Macedonia / Klinika za urologiju,Univerzitetski Klinički centar “Majka Tereza”, Skoplje, Republika Severna Makedonija

 

Abbrevations:
CT-computed tomography.
MRI-magnetic resonance imagining.

 

UDK: 616.62-022.1


The paper was received / Rad primljen: 07.01.2020.

Accepted / Rad prihvaćen: 25.01.2020.

 


Correspondence to:


Ivo Vujichikj,
University Clinic for Urology,
University Clinical Centre “Mother Theresa”,
Skopje,Republic of North Macedonia.
Majka Tereza 17, 1000 Skopje.
Tel.+389 71 269 945.
e-mail: ivovujicic@yahoo.com

 

 

Abstract

 

Introduction: Eosinophilic cystitis is an unusual inflammatory disorder that can cause hematuria. Eosinophilic cystitis usually presents with lower urinary tract symptoms or hematuria which may lead to a diagnosis of urinary tract infections or bladder malignancy. The criterion standard for diagnosis of eosinophilic cystitis is by biopsy with histopathological examination. Case report: We report a rare clinical case of eosinophilic cystitis in an82-year –old man. He presented to urologist with a five-day history of hematuria, dysuria and frequency of urination.An initial ultrasound scan of the urinary tract showed presence of 4 mm tumor mass of the posterior bladder wall, without signs of ureteral obstruction. The contrast CT scan revealed 6 mm hyperdense focus in the bladder, suggestive of bladder lesion. Malignancy was suspected and he was offered an endoscopic treatment option under spinal anesthesia. Transurethral resection biopsy and hemostasis of the bladder wall was done. Microscopic evaluation showed lamina propria with moderate inflammatory infiltrate rich in eosinophils suggestive of eosinophilic cystitis. Conclusion: We reported a clinical case of eosinophilic cystitis diagnosed with transurethral biopsy of bladder in a patient with hematuria. It is important to be aware of this unusual disease, as accurate diagnosis with non-specific medical therapy can prevent possible complications.  

 

Key words:

Cystitis; eosinophilic; hematuria.

 

 

Sažetak

 

Uvod: Eozinofilni cistitis je neobičan upalni poremećaj bešike koji može izazvati hematuriju. Obično se javlja sa simptomima donjeg urinarnog trakta što može pogrešno da nas dovede do dijagnoze infekcije mokraćnih puteva ili maligniteta bešike.Dijagnoza eozinofilnog cistitisa se postavlja na osnovu biopsije bešike sa histopatološkim nalazom. Prikaz slučaja: Prikazujemo redak klinički slučaj eozinofilnog cistitisa kod 82-godišnjeg muškarca. Uputio se kod urologa sa anamnezom petodnevne hematurije, dizurije i učestalim mokrenjem. Ultrazvučni pregled urinarnog trakta pokazao je prisustvo 4 mm tumorske mase zadnjeg zida bešike, bez znakova ureteralne opstrukcije. Kontrastni CT pokazao je 6 mm hiperdenznu promenu, što sugeriše leziju bešike. Posumnjali smo na malignitet i urađena mu je endoskopska intervencija pod spinalnom anestezijom. Urađena je transuretralna biopsija i hemostaza zida bešike. Histopatološki pregled pokazao je laminu propriju sa umerenim upalnim infiltratom eozinofilima koji ukazuje na eozinofilni cistitis. Zaključak: Prikazali smo klinički slučaj eozinofilnog cistitisa dijagnostikovanog transuretralnom biopsijom bešike kod pacijenta sa hematurijom. Važno je da budemo svesni ove retke neobične bolesti jer tačna dijagnoza sa lečenjem nespecifičnom medicinskom terapijom može sprečiti moguće komplikacije.

 

 

Ključne reči:

Cistitis; eozinofilni; hematurija.

 

 

References:

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PDF Vujichikj I. and Penev M. • MD-Medical Data 2020;12(1): 045-047

 

 

 

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