md-medicaldata


Go to content

THE DIFFERENCE IN VENTILATORY DRIVE IN TRAINED AND UNTRAINED PERSONS -SYSTEMATIC REVIEW /

RAZLIKA U VENTILATORNOM NAGONU KOD FIZIČKI AKTIVNIH (UTRENIRANIH) I NEUTRENIRANIH OSOBA - SISTEMSKI PREGLED

Authors

 

Mersudin Mulić1, Biljana Lazović2, Radmila Dmitrović2, Sanja Šarac3, Rade Milić3, Vladimir Zugić 4

1State University Novi Pazar, Serbia
2University clinical center "Zemun", Belgrade, Serbia
3Military Medical Academy, Clinic for pulmonology, Belgrade
4Clinic for lung diseases, Clinical center of Serbia, Belgrade, Serbia, University of Belgrade, Serbia

 

UDK: 613.7:612.217


The paper was received / Rad primljen: 20.02.2020.

Accepted / Rad prihvaćen: 28.02.2020.

 


Correspondence to:


Biljana Lazović
University Clinical Center "Zemun", Belgrade, Serbia
Vukova 9, Zemun, 11080 Belgrade
cell phone +381 62212040

 

 

Abstract

 

Introduction: The  simplified concept of respiratory urge is to consider it as the integrated "exit" from the CNS to the respiratory muscles of the "pump". This urge is a result of a complex central respiratory sample generation, and may occur  in abnormal situations, e.g. of pathological or pharmacological origin, be altered. The ventilatory drive is affected by some factors such as chemosensitivity, basal arterial oxygen or carbon dioxide tension, mechanical impedence and breathing muscle dysfunction. Dulled ventilatory urge or a decrease in the perception of dyspnea in certain conditions could lead to a reduce in the alarm reaction to dangerous situations such as severe airway obstruction, severe hypoxemia, or severe hypercapnia. Aim: The purpose of this systematic review is to obtain differences in respiratory drive among untrained and trained subject.  We have searched Pubmed database and the key words were: respiratory drive. We have thoroughly studied 46 articles. Conclusion: Physical activity plays crucial part in respiratory adaptation, improving respiratory drive which could lead to better and faster response on stronger effort, without fatigue in untrained subjects. To reach respiratory adapatation to stonger stimuli, physical activity must be continuous and intense.

 

 

Key words:

ventilation, trained subjects, CO2, chemoreceptors, exercise

 

 

Sažetak

 

Uvod: Ventilatorni nagon se pojednostavljeno može prikazati kao integrisani, izlazni odgovor centralnog nervnog sistema ka respiratornoj muskulaturi. Ventilatorni nagon predstavlja rezultat kompleksnog generisanja obrazaca respiratornog centra, pri čemu oni mogu biti izmenjeni pod dejstvom patoloških ili farmakoloških faktora .Ovaj sistem je pod direktnim uticajem hemoreceptora, parcijalnog pritiska kiseonika i ugljen dioksida, i zavisi od otpora i eventualne disfunkcije respiratorne muskulature. Njegovo zatajenje ili redukcija percepcije dispnee u okviru pojedinih stanja može voditi neadekvatnoj reakciji na ugrožavajuće situacije poput ozbiljne opstrukcije disajnog puta, teške hipoksemije odnosno hiperkapnije. Cilj: Svrha ovog pregleda je da se dobiju podaci o razlikama respiratornog nagona kod neutreniranih i utreniranih osoba. Pretražili smo Pubmed bazu sa „respiratorni drajv“ kao ključnom reči i detaljno smo proučili 46 članaka. Zaključak: Fizička aktivnost igra značajnu ulogu u respiratornoj adaptaciji. Kao intenzivna i kontinuirana, fizička aktivnost unapređuje ventilatorni nagon i čini odgovor neutreniranih osoba bržim i boljim na teži fizički napor, bez osećaja umora.  Da bi se postigla respiratorna adaptacija na jače podražaje, fizička aktivnost mora biti kontinuirana i intenzivna.

 

 

Ključne reči:

ventilacija, utrenirane osobe, CO2, hemoreceptori,vežbanje.

 

 

References:

  1. Song G, Yu Y, Poon CS. Cytoarchitecture of pneumotaxic integration of respiratory and nonrespiratory information in the rat. J Neurosci. 2006;26(1):300–10.
  2. Lazovic B, Zlatkovic Svenda M, Durmic T, Stajic Z, Duric V, Zugic V. The regulation role of carotid body peripheral chemoreceptors in physiological and pathophysiological conditions. Vol. 69, Medicinski pregled. 2016. p. 385–90.
  3. Vaporidi K, Akoumianaki E, Telias I, Goligher EC, Brochard L, Georgopoulos D. Respiratory Drive in Critically Ill Patients: Pathophysiology and Clinical Implications. Am J Respir Crit Care Med. 2019;
  4. Burton MD, Kazemi H. Neurotransmitters in central respiratory control. Respir Physiol. 2000;122(2–3):111–21.
  5. Durmic T, Lazovic Popovic B, Zlatkovic Svenda M, Djelic M, Zugic V, Gavrilovic T, et al. The training type influence on male elite athletes’ ventilatory function. BMJ Open Sport Exerc Med. 2017;3(1).
  6. Lazovic-Popovic B, Zlatkovic-Svenda M, Durmic T, Djelic M, Djordjevic Saranovic S, Zugic V. Superior lung capacity in swimmers: Some questions, more answers! Rev Port Pneumol . 2016;22(3):151–6.
  7. Durmic T, Lazovic B, Djelic M, Lazic JS, Zikic D, Zugic V, et al. Sport-specific influences on respiratory patterns in elite athletes. J Bras Pneumol. 2015;41(6):516–22.
  8. Pezelj L, Milavic B, Erceg M. Respiratory parameters in elite finn-class sailors. Montenegrin J Sport Sci Med. 2019;8(1):5–9.
  9. Mazic S, Lazovic B, Djelic M, Suzic-Lazic J, Djordjevic-Saranovic S, Durmic T, et al. Respiratory parameters in elite athletes - does sport have an influence? Rev Port Pneumol. 2015;21(4):192–7.
  10. Ivanovic M, Petrovic J, Miletic M, Danicic A, Bojovic B, Vukcevic M, et al. Rib-cage-movement measurements as a potential new trigger signal in non-invasive mechanical ventilation. In: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Institute of Electrical and Electronics Engineers Inc.; 2015. p. 4511–4.
  11. Shea SA, Andres LP, Shannon DC, Banzett RB. Ventilatory responses to exercise in humans lacking ventilatory chemosensitivity. J Physiol. 1993;468(1):623–40.
  12. Whitelaw WA, Derenne JP, Milic-Emili J. Occlusion pressure as a measure of respiratory center output cm conscious man. Respir Physiol. 1975;23(2):181–99.
  13. Daley MA, Bramble DM, Carrier DR. Impact Loading and Locomotor-Respiratory Coordination Significantly Influence Breathing Dynamics in Running Humans. Hug F, editor. PLoS One. 2013;8(8):e70752.
  14. Smith CA, Blain GM, Henderson KS, Dempsey JA. Peripheral chemoreceptors determine the respiratory sensitivity of central chemoreceptors to CO2: Role of carotid body CO2. J Physiol. 2015;593(18):4225–43.
  15. Lalley PM. μ-opioid receptor agonist effects on medullary respiratory neurons in the cat: Evidence for involvement in certain types of ventilatory disturbances. Am J Physiol - Regul Integr Comp Physiol. 2003;285(6 54-6).
  16. Adler D, Janssens JP. The pathophysiology of respiratory failure: Control of breathing, respiratory load, and muscle capacity. Vol. 97, Respiration. S. Karger AG; 2019. p. 93–104.
  17. Aliverti A, Dellacà RL, Lotti P, Bertini S, Duranti R, Scano G, et al. Influence of expiratory flow-limitation during exercise on systemic oxygen delivery in humans. Eur J Appl Physiol. 2005;95(2–3):229–42.
  18. Durmić T, Djelić M, Suzić Lazić J, Lazović Popović B, Dekleva M, Soldatovic I, et al. Insights into body composition adaptation: Should we reconsider the use of Body Mass Index in some sports? J Sports Med Phys Fitness. 2016;56(11):1331–8.
  19. Verges S, Lenherr O, Haner AC, Schulz C, Spengler CM. Increased fatigue resistance of respiratory muscles during exercise after respiratory muscle endurance training. Am J Physiol - Regul Integr Comp Physiol. 2007;292(3).
  20. Dempsey JA, Wagner PD. Exercise-induced arterial hypoxemia. Vol. 87, Journal of Applied Physiology. 1999. p. 1997–2006.
  21. Hill A V., Long CNH, Lupton H. Muscular Exercise, Lactic Acid and the Supply and Utilisation of Oxygen. Proc R Soc B Biol Sci. 1924;97(682):155–76.
  22. Wasserman K, Hansen JE, Sue DY, Stringer WW, Whipp BJ. Physiology of exercise. In: Wasserman K, Hansen JE, Sue DY, Stringer WW, Sietsema KE, Sun X-G, et al., editors. Principles of Exercise Testing and Interpretation: Including Pathophysiology and Clinical Applications. Philadelphia: Lippincott Williams & Wilkins; 2004. p. 10–65.
  23. Mazic S, Suzic Lazic J, Dekleva M, Antic M, Soldatovic I, Djelic M, et al. The impact of elevated blood pressure on exercise capacity in elite athletes. Int J Cardiol. 2015;180:171–7.
  24. Mazić S, Lazović B, Delić M, Lazić JS uzi., Aćimović T, Brkić P. Body composition assessment in athletes: a systematic review. Vol. 67, Medicinski pregled. 2014. p. 255–60.

PDF Mulić M. et al • MD-Medical Data 2020;12(1): 011-014

 

 

 

Naslovna | Revija | Galerija | Dešavanja | Instrukcije | Redakcija | Izdavač | Prijatelji sajta | Saradnja | Kontakt | Site Map


Back to content | Back to main menu