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PAPILARNI FIBROELASTOMI SRCA – DESETOGODIŠNJE ISKUSTVO INSTITUTA ZA KARDIOVASKULARNE BOLESTI VOJVODINE U SREMSKOJ KAMENICI /
PAPILARY FIBROELASTOMA OF THE HEART – 10 YEARS EXPERIENCE FROM INSTITUTE OF CARDIOVASCULAR DISEASES, SREMSKA KAMENICA

Authors

 

Golub Samardžija1,2, Milan Popović3, Aleksadra Lovrenski1,4, Dejan Miljković3, Dragana Tegeltija1,4

1Univerzitet u Novom Sadu, Medicinski fakultet, Katedra za patologiju
2Institut za kardiovaskularne bolesti Vojvodine, Sremska Kamenica
3Univerzitet u Novom Sadu, Medicinski fakultet, Katedra za histologiju i embriologiju
4Služba za patološko-anatomsku i molekularnu dijagnostiku, Institut za plućne bolesti Vojvodine, Sremska Kamenica

 

UDK: 616.12-006.327(497.113)


The paper was received / Rad primljen: 22.06.2019.

Accepted / Rad prihvaćen: 30.06.2019

 


Autor za korespondenciju:


doc. dr Golub Samardžija
Katedra za patologiju
Medicinski fakultet, Univerzitet u Novom Sadu
Hajduk Veljkova 3, 21 000 Novi Sad
Tel.: +381642131080
e-mail: golub.samardzija@mf.uns.ac.rs

 

 

Sažetak

 

Papilarni fibroelastom (PFE) je redak, benigni tumor koji predstavlja manje od 10% primarnih srčanih tumora. U 90% slučajeva javlja se na srčanim zaliscima. Serije autopsija pokazuju ravnopravnost distribucije desnog i levog srca, dok hirurške serije imaju visoku prevalencu levostranog PFE.Ehokardiografija, CT i MR srca su najčešće korišćene dijagnognostičke metode, ali ipak za tačnu dijagnostiku tumora srca neophodna je patohistološka analiza. Istraživanje je sprovedeno na Institutu za kardiovaskularne bolesti Vojvodine u Sremskoj Kamenici. Studija je bila retrospektivna i obuhvatala je period od januara 2008. do septembra 2017. godine. U studiju je bilo uključeno14 pacijenata kod kojih je zbog dijagnostikovanog tumora srca izvršena ekstirpacija tumora u celosti. U našem istraživanju 31% su činili muškarci, dok su udeo od 69% zauzimale osobe ženskog pola. Samo jedanpacijent je bio bez tegoba, dok je najveći broj pacijenata je osetilo nedostatak vazduha i gušenje kao glavni simptom (26%). Najčešća lokalizacija tumora je na aortnoj valvuli 50%, zatim na mitralnoj valvuli 29%, levoj pretkomori 7%, levoj komori 7% i trikuspidalnoj valvuli 7%. Prosečna veličina tumora kod EHO nalaza je 0,94 cm, a kod patološkog nalaza 0,84 cm. Iako papilarni fibroelastomi predstavljaju retke benigne tumore srca mogu izazvati ozbiljne životno ugrožavajuće komplikacije.

 

 

Ključne reči:

papilarni fibroelastomi, benigni tumori, srce

 

 

Abstract

 

Papillary fibroelastoma (PFE) is a rare, benign tumor that represents less than 10% of primary heart tumors. In 90% of cases, it can be found in the heart valves. The series of autopsy show the equality of distribution of the right and left heart PFE, while the surgical series have a high prevalence of left heart PFE. Echocardiography, CT and MRI of heart are the most commonly used diagnostic methods, but for the accurate diagnosis of tumors of the heart, a pathohistological analysis is golden standard. This research was conducted at the Institute for Cardiovascular Diseases of Vojvodina in Sremska Kamenica. The study was retrospective and covered the period from January 2008 to September 2017. In the study, 14 patients were included due to a diagnosed heart tumor. In our study, 31% of patients were men, while 69% of patients were women. Only one patient didn’t have any manifeatation of illness, while the majority of patients felt a lack of air and choking as the main symptoms (26%). The most common tumor localization was the aortic valve - 50%, then the mitral valve - 29%, in the left atrial septum - 7%, in the left ventricle - 7%, and  the tricuspid valve - 7%. The average tumor size in the EHO findings was 0.94 cm, and in the pathological finding was 0.84 cm. Although papillary fibroelastomas are very rare benign tumors of the heart, they can cause serious life-threatening complications.

 

 

Keywords:

papillary fibroelastoma, benign tumor, heart

 

 

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PDF Samardžija G. et al. • MD-Medical Data 2019;11(2): 087-091

 

 

 

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