md-medicaldata


Go to content

UČESTALOST I DISTRIBUCIJA MALIGNIH TUMORA MOZGA I CENTRALNOG NERVNOG SISTEMA ODRASLOG STANOVNIŠTVA MAČVANSKOG OKRUGA, 2006-2015 /
THE INCIDENCE FREQUENCY AND DISTRIBUTION OF BRAIN AND CENTRAL NERVOUS SYSTEM CANCERS IN ADULT POPULATION IN THE MAČVA DISTRICT, 2006-2015

Authors

 

Marijana Srećković1, Tihomir Dugandžija2,3, Dušan Backović4, Nataša Hinić2,3, Zoran Jovanović1,5, Ljubica Pajić Nikolić1, Igor Dragičević6

1Visoka medicinska i poslovno-tehnološka škola strukovnih studija u Šapcu, Srbija
2Medicinski fakultet, Univerzitet u Novom Sadu, Srbija
3Institut za onkologiju Vojvodine, Sremska Kamenica, Serbia
4Institut za higijenu i medicinsku ekologiju, Medicinski fakultet, Univerzitet u Beogradu
5Opšta bolnica „Dr Laza K. Lazarević” Šabac, Srbija
6Zavod za javno zdravlje Šabac, Srbija

 

616.83-006.04(497.11)”2006/2015”


The paper was received / Rad primljen: 23.04.2019.

Accepted / Rad prihvaćen: 02.05.2019.

 


Correspondence to:


dr Marijana Srećković
Visoka medicinska i poslovno-tehnološka škola strukovnih studija u Šapcu
kontakt telefon: 063-836-98-98
Hajduk Veljkova br.10; 15000 Šabac
e-mail: drsreckovicmaja@gmail.com

 

 

Sažetak

 

Uvod: Maligni tumori mozga i centralnog nervnog sistema (C70-72) predstavljaju manje od 3% novodijagnostikovanih slučajeva malignih bolesti, ali sa sve izraženijom tendencijom porasta incidencije kod muškaraca. Geografsko-demografske varijacije javljanja ovih tumora još uvek nisu dovoljno razjašnjene.
Cilj: Da se opišu topografsko-demografske varijacije C70-72 kod odraslog stanovništva na teritoriji Mačvanskog okruga tokom 10 uzastopnih godina posmatranja (2006-2015).
Materijal i metode: Retrospektivnom analizom podataka Zavoda za javno zdravlje Šabac o C70-72, predstavljen je desetogodišnji linearni trend kretanja standardizovanih stopa incidencije (age-standardised rate-ASR World) i uzrasno-specifične stope incidencije (age-specific incidence rates) kod odraslog stanovništva.
Rezultati: Prosečne desetogodišnje ASR za C70-72 kod muškaraca i žena iznosile su 6,7 naspram 5 na 100 000 stanovnika. Uočene su visoke ASR za C70-72 kod muškaraca starijih od 20 godina u opštini Ljubovija u odnosu na muškarce istog uzrasta na teritoriji drugih opština Mačvanskog okruga. Među muškarcima, razlike ASR za C70-72 bile su veće u opštini Ljubovija u odnosu na opštine Loznica i Šabac. Uzrasno-specifične stope incidencije pokazuju pik obolevanja u uzrastu od 60-64 godine života kod oba pola.
Zaključak: Uočene topografsko-geografske varijacije i polne razlike u stopama incidencije zabeležene su kod odraslog stanovništva na teritoriji Mačvanskog okruga.

 

 

Ključne reči:

maligni tumori mozga i centralnog nervnog sistema, standardizovane stope incidencije, uzrasno-specifične stope incidencije

 

 

Abstract

 

Introduction: Malignant tumors of the brain and central nervous system (C70-72) represent less than 3% of new diagnosed cases of malignant disease, but with a growing tendency of an increase in incidence in males. Geographic and demographic variations in the occurrence of these tumors have not yet been sufficiently clarified.
Objective: To describe the C70-72 topographic and demographic variations in the adult population in the territory of the Mačva District during the 10 consecutive years of observation (2006-2015).
Material and methods: A retrospective data analysis from the Šabac Public Health Institute of C70-72 represents a ten-year linear trend in the movement of age-standardized rate (ASR World) and age-specific incidence rates in the adult population
Results: The average 10-year ASRs of C70-72 in males and females were 6.7 and 5.0 per 100 000 inhabitants, respectively. High ASRs of C70-72 was observed in males above 20 years of age in Ljubovija compared to men of the same age group on the territory of other municipalities of the Mačva District. Among males differences in ASRs of C70-72 was higher in municipality Ljubovija compared to municipalities Loznica i Šabac. Age-specific incidence rates showed a peak of disease at the age of 60-64 years of life with both sexes.
Conclusion: Noticeable topographic and geographic variations and sex disparity in incidence rates were observed in the adult population of the Mačva District.

 

 

Keywords:

brain and central nervous system cancers, standardized incidence rates, age-specific incidence rates

 

 

References:

 

  1. Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015 Mar 1;136(5):E359-86. Epub 2014 Oct 9.
  2. GLOBOCAN. Estimated age-standardized incidence rates (World) in 2018, brain, central nervous system, males, ages 20+: International Agency for Research on Cancer, World Health Organization, 2018. Available from: http://globocan.iarc.fr.
  3. Darefsky AS, Dubrow R. International variation in the incidence of adult primary malignant neoplasms of the brain and central nervous system. Cancer Causes Control. 2009 Nov; 20(9):1593-604. Epub 2009 Jul 25.
  4. CANCER TOMORROW. Estimated number of incident cases from 2018 to 2040, brain, central nervous system, males and females, all ages: International Agency for Research on Cancer, World Health Organization, 2018. Available from: http://globocan.iarc.fr.
  5. Incidеnciја i mоrtаlitеt оd rаkа u Cеntrаlnој Srbiјi. Beograd: Institut za javno zdravlje Srbije “Dr Milan Jovanović Batut”, 2012. Dostupno na:http://www.batut.org.rs/index.php?content=185.
  6. Fisher JL, Schwartzbaum JA, Wrensch M, Wiemels JL. Epidemiology of brain tumors, Neurol Clin. 2007 Nov;25(4):867-90,VII.
  7. Ostrom QT, Bauchet L, Davis FG, Deltour I, Fisher JL, Langer CE, et al. The epidemiology of glioma in adults: a state of the science review, Neuro Oncol. 2014 Jul;16(7):896-913.
  8. Braganza MZ, Kitahara CM, Berrington de González A, Inskip PD, Johnson KJ, Rajaraman P. Ionizing radiation and the risk of brain and central nervous system tumors: a systematic review. Neuro Oncol. 2012;14(11):1316–1324.
  9. Sadetzki S, Chetrit A, Freedman L, Stovall M, Modan B, and Novikov I. Long-Term Follow-up for Brain Tumor Development after Childhood Exposure to Ionizing Radiation for Tinea Capitis. Radiation Research: April 2005, Vol. 163, No. 4, pp. 424-432.
  10. Acquavella J, Olsen G, Cole P, Ireland B, Kaneene J, Schuman S, et al. Cancer among farmers: a meta-analysis. Ann Epidemiol 1998;8:64–74.
  11. Khuder SA, Mutgi AB, Schaub EA. Meta-analyses of brain cancer and farming. Am J Ind Med. 1998;34:252–60.
  12. Provost D, Cantagrel A, Lebailly P, Jaffre´ A, Loyant V, Loiseau H, et al. Brain tumors and exposure to pesticides: a case-control study in southwestern France. Occup Environ Med. 2007;64:509–14.
  13. Dugandžija T. Onkološka epidemiologija. Medicinski fakultet [monografija]. Univerzitet u Novom Sadu, Medicinski fakultet; 2018.
  14. Van Maele-Fabry G, Hoet P, Lison D. Parental occupational exposure to pesticides as risk factor for brain tumors in children and young adults: a systematic review and metaanalysis. Environ Int. 2013;56:19–31.
  1. 15.Mrđenovački O. N. Pokazatelji zdravstvenog stanja stanovništva i stanja životne sredine Mačvanskog okruga. Zavod za javno zdravlje Šabac. Dostupno na: http://www.zjz.org.rs/wp-content/uploads/2013/09/POKAZATELJI-ZDRAVSTVENOG-STANJA-STANOVNI%C5%A0TVA-MA%C4%8CVANSKOG-OKRUGA.pdf.
  1. Republički zavod za statistiku, Republika Srbija, popis stanovništva 2011. godine. Dostupno na:  http://www.stat.gov.rs/sr-latn/oblasti/popis/popis-2011/popisni-podaci-eksel-tabele/ .
  2. Forman D, Bray F, Brewster DH, Mbalawa CG, Kohler B, Piñeros M, et al. Cancer Incidence in Five Continents: Inclusion criteria, highlights from Volume X and the global status of cancer registration. Int J Cancer. 2015 Nov 1;137(9):2060-71.
  3. Piñeros M, Sierra MS, Izarzugaza MI, Forman D. Descriptive epidemiology of brain and central nervous system cancers in Central and South America. Cancer Epidemiol. 2016 Sep;44 Suppl 1:S141-S149.
  4. Lee WJ, Colt JS, Heineman EF, McComb R, Weisenburger DD, Lijinsky W, et al. Agricultural pesticide use and risk of glioma in Nebraska, United States. Occup Environ Med. 2005 Nov;62(11):786-92.
  5. Chrisman Jde R, Koifman S, de Novaes Sarcinelli P, Moreira JC, Koifman RJ, Meyer A. Pesticide sales and adult male cancer mortality in Brazil. Int J Hyg Environ Health. 2009 May;212(3):310-21. Epub 2008 Oct 1.
  6. Miranda Filho AL, Koifman RJ, Koifman S, Monteiro GT. Brain cancer mortality in an agricultural and a metropolitan region of Rio de Janeiro, Brazil: a population-based, age-period-cohort study, 1996-2010. BMC Cancer. 2014;14:320. Published 2014 May 6.
  7. Carles C, Bouvier G, Esquirol Y, Piel C, Migault L, Pouchieu C, et al. Residential proximity to agricultural land and risk of brain tumor in the general population. Environ Res. 2017 Nov;159:321-330. Epub 2017 Sep 18.
  8. Pouchieu C, Baldi I, Gruber A, Berteaud E, Carles C, Loiseau H. Descriptive epidemiology and risk factors of primary central nervous system tumors: Current knowledge. Rev Neurol (Paris). 2016 Jan;172(1):46-55.
  9. Vidojević D, Baćanović N, Dimić D. 2015: Izveštaj o stanju zemljišta za 2013. godinu. Ministarsvo poljoprivrede i zaštite životne sredine, Agencija za zaštitu životne sredine, ISSN 2334-9913.
  10. Mrvić V, Antonović G, Martinović Lj, 2009: Plodnost i sadržaj opasnih i štetnih materija u zemljištima centralne Srbije, Institut za zemljište, Beograd, (ISBN 978-86-911273-1-2).

PDF Marijana Srećković • MD-Medical Data 2018;10(4): 173-177

 

 

 

Naslovna | Revija | Galerija | Dešavanja | Instrukcije | Redakcija | Izdavač | Prijatelji sajta | Saradnja | Kontakt | Site Map


Back to content | Back to main menu