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MULTICYSTIC DYSPLASTIC KIDNEY – CASE REPORT
MULTICISTIČNA RENALNA DISPLAZIJA - PRIKAZ SLUČAJA

Authors

 

Matilda Đolai1,2, Ilić Sabo Jabo1,2, Sandra Trivunić Dajko1,3, Tanja Lakić1,3, B. Krajinović2, Željka Vrekić2

11Katedra za histologiju i embriologiju, Madicinski fakultet, Univerzitet Novi Sad. 2Centar za patologiju i histologiju, Klinički centar Novi Sad. 3Katedra za patologiju, Madicinski fakultet, Univerzitet Novi Sad.

 

UDK: 616.61


The paper was received / Rad primljen: 16.08.2018.

Accepted / Rad prihvaćen: 28.08.2018.

 


Correspondence to:


Prof. dr Matilda Đolai
Univerzitet Novi Sad.
Katedra za histologiju i embriologiju, Madicinski fakultet,
Centar za patologiju i histologiju,
Klinički centar Novi Sad. Hajduk Veljkova 1-3, 21000 Novi Sad.
e-mail: matilda.djolai@mf.uns.ac.rs

 

 

Abstract

 

Multicystic dysplastic kidney is a congenital anomaly followed by structural disintegration and cystic like changes of kidney shape. This paper presents case of multicystic dysplastic kidney in fetus five months old. By external examination, micrognatia was observed. By internal examination were founded enlargement of lateral cerebral ventricles, macroscopically altered kidneys and hypoplastic bladder. At the place of the left kidney there was a small, rounded, irregular structure, lobulated surface, with diameter 3 mm, while at the place of the right kidney was cyst formation of the same dimension. Both ureters were the corresponding macroscopic properties. Histological analysis of the described structure showed the kidney with abnormal differentiation followed by the primitive glomeruls and tubules, and by cystic dilatation of nephrons. The renal malformation was diagnosed as the multicystic renal dysplasia. Bilateral multicystic dysplastic kidney is a rare anomaly incompatible with life, and its association with malformation of the brain ventricular system is especially rare.

 

 

Keywords:

Dysplasia, kidney, malformations, fetus.

 

 

Sažetak

 

Multicistična renalna displazija je urodjena (kongenitalna) malformacija bubrega koju karakteriše strukturalna dezintegracija bubrežnog parenhima i cističan izgled bubrega. U radu je prikazan slučaj multicistične renalne displazije kod fetusa starosti pet lunarnih meseci. Pregledom ploda od spoljašnjih malformacija nadjena je samo mikrognatija. Unutrašnjim preglednom fetusa nadjena je obostrana dilatacija obe moždane komore, narušena i cistična struktura oba bubrega i hipoplazija mokraćne bešike. Na mestu levog bubega nadjena je mala, iregularna, ovalna struktura, lobulirane površine i prečnika 3mm, dok je na mestu desnog bubrega nadjena mala, policistična formacija, prečnika 3mm. Oba uretera su očuvanih makroskopskih karakteritika. Histološkom analizom tkivnih uzoraka sa mesta bubrega, uočeno je da se nalazi bubrežni parenhim sa primitivnim glomerulima i tubulima i cistična dilatacija nefrona i malformacija je nazvana bilateralna multicitična renalna displazija. Bilateralna multicistična displazija je retka malformacija koja je inkopatibilna sa ivotom. Prema literaturnim podacima udruženost ove malformacije sa malformacijama ventrikularnog sistema moždanih ventrikula je izuzetno retka.

 

 

Ključne reči:

Displazija, bubreg, malformacije, fetus

 

 

References:

 

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PDF Đolai M. et al. • MD-Medical Data 2018;10(3): 159-161

 

 

 

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