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CIP -  Каталогизација у публикацији
Народна библиотека Србије, Београд
61
MD : Medical Data : medicinska revija = medical review / glavni i odgovorni urednik Dušan Lalošević. - Vol. 1, no. 1 (2009)- . - Zemun : Udruženje za kulturu povezivanja Most Art Jugoslavija ; Novi Sad : Pasterovo društvo, 2009- (Beograd : Scripta Internacional). - 30 cm

Dostupno i na: http://www.md-medicaldata.com. - Tri puta godišnje.

ISSN 1821-1585 = MD. Medical Data
COBISS.SR-ID 158558988


SYNCHRONOUS ENDOCRINE MICROADENOMATOSIS WITH WELL DIFFERENTIATED NEUROENDOCRINE TUMOR OF PANCREAS /
ENDOKRINA MIKROADENOMATOZA SA NEUROENDOKRINIM TUMOROM PANKREASA

Authors

 

Aleksandra Ilić1, Sandra Trivunić Dajko1,2, Mirjana Živojinov1,2, Jelena Amidžić1,3, Jelena Ilić Sabo1,3, Tanja Lakić1,2, Aleksandra Fejsa Levakov1,3, Matilda Đolai1,3

1Center for Pathology and Histology, Clinical Center of Vojvodina Novi Sad
2Department of Pathology, Medical Faculty Novi Sad, University of Novi Sad
3Department of Histology and Embryology, Medical Faculty Novi Sad, University of Novi Sad

 

UDK: 616.37-006.5


The paper was received 02.02.218. Accepted: 04.03.2018.

Rad primljen 02.02.218. Rad prihvaćen: 04.03.2018.

 


Corresponding author/ Autor za korespodenciju:


Dr Aleksandra Ilić
Center for Pathology and Histology, Clinical Center of Vojvodina Novi Sad
Hajduk Veljkova 3, 21000 Novi Sad
Tel: 0691452582
e-mail: alilic91@gmail.com

 

 

Abstract

 

Introduction: Endocrine microadenomatosis is defined as the presence of multiple, usually innumerable, microadenomas. Endocrine microadenoma is a neuroendocrine neoplasm measuring less than 5mm in size.
Case report: This article showed pathohistological case report of pancreatic endocrine microadenomatosis in addition to synchronous well differentiated neuroendocrine tumor of the pancreas in 49-year-old female patient. Histological appearance of tumor was typical and was positive to neuroendocrine immunohistochemical antibodies.
Conclusion: Pancreatic endocrine microadenomatosis in addition to synchronous well differentiated neuroendocrine tumor of the pancreas is rare, so this case is presented.

 

 

Key words:

pancreas, microadenomatosis, NET

 

 

Sažetak

 

Uvod: Endokrina mikroadenomatoza pankreasa predstavlja pojavu brojnih mikroadenoma porekla neuroendokrinih ćelija, koji su po definiciji prečnika do 5mm.
Prikaz slučaja: U ovom članku je prikazan patohistološki slučaj mikroadenomatoze sa sinhronim dobro diferentovanim neuroendokrinim tumorom pankreasa kod pacijenta ženskog pola, starosti 49 godina. Histološka slika tumora i imunohistohemijski profil ćelija su bili tipični za navedene neuroendokrine lezije.
Zaključak: Endokrina mikroadenomatoza pankreasa sa sinhronim dobro diferentovanim neuroendokrinim tumorom je niske incidence i otuda je odabrana za prikaz slučaja.

 

 

Ključne reči:

pankreas, mikroadenomatoza, NET

 

 

Reference / Literatura

 

  1. Campbell F, Verbeke C. Pathology of the pancreas a practical approach. London: Springer; 2013.
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  3. Pham H. Pancreatic Neuroendocrine Tumor: Genetic Signatures. TTU Review. 2016;1(2).
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  5. Singhi AD, Klimstra DS. Well differentiated pancreatic neuroendocrine tumours (PanNETs) and poorly differentiated pancreatic neuroendocrine carcinomas (PanNECs): concepts, issues and a practical diagnostic approach to highgrade (G3) cases. Histopathology. 2018;72(1):168-77.
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  8. Rindi G, Solcia E. Endocrine hyperplasia and dysplasia in the pathogenesis of gastrointestinal and pancreatic endocrine tumors. Gastroenterol Clin North Am 2007; 36: 851-865, vi
  9. Yu R, Nissen NN, Dhall D, Heaney AP. Nesidioblastosis and hyperplasia of α cells, microglucagonoma, and nonfunctioning islet cell tumor of the pancreas: review of the literature. Pancreas. 2008;36(4):428-31.
  10. Anlauf M, Schlenger R, Perren A, Bauersfeld J, Koch CA, Dralle H, Raffel A, Knoefel WT, Weihe E, Ruszniewski P, Couvelard A. Microadenomatosis of the endocrine pancreas in patients with and without the multiple endocrine neoplasia type 1 syndrome. The Am J Surg Pathol. 2006;30(5):560-74.
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PDF Ilić A. et al. • MD-Medical Data 2018;10(1): 059-062

 

 

 

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