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HERBAL MEDICINE IN ACUTE RESPIRATORY INFECTIONS
BILJNI PROIZVODI U LEČENJU AKUTNIH RESPIRATORNIH INFEKCIJA

Authors

 

Aneta Agić1, Davor Korčok1, Biljana Lazovic2

1Abela Pharm, Belgrade, Serbia,
2Clinical Hospital Center Zemun, Belgrade, Serbia

 


Rad je primljen 27.08.2017. / Prihvaćen 11.12.2017.

 


Correspondence to


Dr sci. med. Biljana Lazović,
KBC „Zemun“, Ul. Vukova 9, 11 000 Beograd
Telefon: +381 62 212 040
e-mail: lazovic.biljana@gmail.com

 

 

Abstract

 

Introduction and aim: Herbal expectorants and secretolytic agents hold a sizeable share of the European market. Therefore it is essential to test their clinical effectiveness and safety. It has been know from centuries that herbal products have long been recognized to have an important role in natural defense of respiratory disease from various exogenous toxins. In order to clarify the possible role of N-acetylcysteine (NAC) in the treatment of acute respiratory infections or exacerbations of chronics ones, we have carried out a study to assess the efficiency and safety of PropoMucil® in patients with various respiratory disease.
Matherial and method: The study was conducted from December 2016 to March 2017 in Belgrade, Serbia in five health care centers. The study included 904 patients suffered from various respiratory disease. All patients receivved natural products N-acetylcysteine combined with propolis to their additional therapy. We followed their symptoms on day 7th, 14th and after month ago.
Results: On the basis of the present assays, N-acetylcysteine combined with propolis (Propomucil®) have shown reduction of cough and mucus secretions in more than half patients on 7th day of usage of therapy. More than half patients (67,5%), on the 7th day check up had improvement in sputum production and its relieved. After a month of therapy with Propomucil®, only 7% have problems with persistent cough.
Conclusion: The study contributed to the evaluation of phytotherapy as a therapy of choice for relieve respiratory symptoms and its prevention. Results from our study have shown immense benefit (by reducing cough and dilution of sputum) of usage PropoMucil® in various respiratory disease.

 

 

 

Key words:

mucus, cough, mucociliary clearance, secretolytic agents, pharmacological effect.

 

 

Sažetak

 

Uvod: Biljni ekspektoransi i sekretolitički agensi imaju značajan udeo u evropskom tržištu. Zbog toga je neophodno testirati njihovu kliničku efikasnost i sigurnost. Od davnina je poznato da biljni proizvodi imaju protektivnu ulogu u respiratornom sistemu. Da bi se razjasnila moguća uloga N-acetilcisteina u lečenju akutnih respiratornih infekcija ili pogoršanja postojećih hroničnih, ovom studijom testirali smo efikasnost i sigurnost preparata Propomucil® u gore navedenim oboljenjima.
Materijal i metode: Studijom je obuhvaćeno ukupno 904 pacijenta koji su lečeni od različitih respiratornih oboljenja u 5 zdravstvenih centara u periodu od decembra 2016. godine do marta 2017. godine. Svaki pacijent je pored osnovne terapije dobio i dodatnu u vidu Propomucil®-a. Simptomi bolesti su praćeni nakon 7, 14 ili mesec dana terapije.
Rezultati: Smanjenje kašlja i mukozne sekrecije registrovano je već 7 dana od početka terapije kod više od pola ispitivanih pacijenata. Takođe, kod više od pola ispitivanih pacijenata (67,5%) pokazalo se poboljšanje u produkciji sputuma i njegovoj eliminaciji, pri čemu su se pacijenti značajno bolje osećali. Kod samo 7% pacijenata, nakon primenjene terapije, zadržao se kašalj.
Zaključak: Sprovedena studija doprinela je oceni fitoterapije kao terapije izbora za ublažavanje respiratornih simptoma. Rezultati naše studije pokazali su dobrobit (smanjenje kašlja i viskoznosti sputuma) upotrebom Propomucil®-a već 7.-og dana terapije kod obolelih od akutnih ili pogoršanja hroničnih respiratornih oboljenja.

 

 

Ključne reči:

sekret, kašalj, mukocilijarni klirens, sekretolitik, farmakološki efekti.

 

 

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PDF Agić A. et al • MD-Medical Data 2017;9(4): 213-218

 

 

 

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