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KARAKTERISTIKE BIHEJVIORALNOG FENOTIPA DAUNOVOG SINDROMA
CHARACTERISTICS OF DOWN SYNDROME BEHAVIORAL PHENOTYPE

Authors

 

Milan Obrenović1, Boris Privrodski2, Ivana Kavečan 3,4, Radojica Savić3,4, Jadranka Jovanović 3,4, Milenko Kolarski 5

1Kabinet za molekularnu genetiku, Institut za zdravstvenu zaštitu dece i omladine Vojvodine, Novi Sad
2Klinika za dečiju hirurgiju, Institut za zdravstvenu zaštitu dece i omladine Vojvodine, Novi Sad
3Medicinski fakultet, Univerzitet u Novom Sadu
4Odeljenje za medicinsku genetiku, Institut za zdravstvenu zaštitu dece i omladine Vojvodine, Novi Sad
5Kabinet za planiranje porodice, Institut za zdravstvenu zaštitu dece i omladine Vojvodine, Novi Sad

 


Rad je primljen 13.08.2017. / Prihvaćen 28.08.2017

 


Correspondence to


Doc. dr Ivana Kavečan,
Univerzitet u Novom Sadu, Medicinski fakultet,
University of Novi Sad, Faculty of Medicine
Institut za zdravstvenu zaštitu dece i omladine Vojvodine
Hajduk Veljkova 3
21000 Novi Sad, Srbija
tel. 021 4880444
mob. tel. +381 63 580 552;
fax: +381 21 4722960
e-mail: ivana.kavecan@mf.uns.ac.rs

 

 

Sažetak

 

Uvod: Osobe sa Daunovim sindromom (DS) pokazuju specifičan bihejvioralni fenotip. Cilj rada: Utvrđivanje individualnih razlika bihejvioralnog fenotipa osoba zahvaćenih DS. Materijal i metode: Retrospektivnom studijom obuhvaćeni su podaci Službe medicinske genetike u sedmogodišnjem periodu (2009-2016. godina). Analizirana je medicinska dokumentacija osoba sa DS koje su dijagnostikovane i kontrolišu se u Službi za medicinsku genetiku i kod kojih je sprovođen habilitacioni tretman i redovna testiranja kognitivnih sposobnosti. Rezultati: Rezultati su prikazani metodama deskriptivne statistike. Analiziran je psihomotorni razvoj 42 dece sa DS u uzrastu odojčeta, malog deteta i predškolskog deteta u više navrata. U uzrastu 3-6 meseci života prosečan kvocijent inteligencije (QI) bio je: 67. U uzrastu 6-12 meseci prosečan QI: 65. U uzrastu od 1-3 godine prosečan QI iznosio je: 58. U uzrastu 3-6 godina: 41. U ispitivanoj grupi utvrđeno je postojanje individualnih razlika osoba sa Daunovim sindromom u uzrastu 3 meseca, najniži kvocijent inteligencije iznosio je 32, a najviši 81. U uzrastu 6-12 meseci, najniži QI je iznosio 30, najviši 84, u uzrastu 1-3 godine najniži QI iznosio je 30, najviši 81, u uzrastu 3-6 godina, najniži QI manje od 20, najviši 58. Zaključak: Osobe sa Daunovim sindromom pokazuju individualne razlike u kvocijentu inteligencije i postignućima na planu koordinacije, motoričkih sposobnosti, razvoja govora i ispoljavanju društvenosti.

 

 

 

Ključne reči:

Daunov sindrom, bihejvioralni fenotip, mentalna nedovoljna razvijenost, razvojni obrazac, rane intervencije

 

 

Abstract

 

Introduction: People with Down syndrome show a specific behavioral phenotype. Objective: Determination of individual differences in behavioral phenotype among persons affected by Down's syndrome. Material and Methods: The retrospective study includes the data of the Medical Genetics Service in a seven-years period (2009-2016). The medical documentation of persons with Down syndrome who were diagnosed and controlled in the Department of Medical Genetics in which habilitation treatment and regular cognitive tests were performed were analyzed. Results: Results are presented by descriptive statistics. The psychomotor development of 42 children with DS in the age of infants, small children and preschool children were analyzed on several occasions. At the age of 3-6 months of life, the average QI was: 67. At the age of 6-12 months, the average QI was 65. At the age of 1-3, the average QI was 58. At the age of 3-6 years: 41. In the investigated group, the existence of individual differences in people with Down syndrome at the age of 3 months was determined; the lowest quotient of intelligence was 32, and the highest 81. At the age of 6-12 months, the lowest QI was 30, the highest 84, At the age of 1-3, the lowest QI was 30, the highest 81, at the age of 3-6 years, the lowest QI less than 20, the highest 58. Conclusion: People with Down syndrome show individual differences in the intelligence quotient and achievements on the plan of coordination, motor skills, speech development, and appearance of sociability.

 

 

Key words:

Down syndrome, behavioral phenotype, intellectual disability, developmental framework, early intervention

 

 

References

 

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UDK: 616.899.6
COBISS.SR-ID 245421836



PDF Obrenović M. et al • MD-Medical Data 2017;9(3): 161-165

 

 

 

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