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EFIKASNOST PRIMENE PROPOLISA I N-ACETILCISTEINA U LEČENJU AKUTNIH RESPIRATORNIH INFEKCIJA KOD DECE
EFFICIENCY OF PROPOLIS AND N-ACETYLCISTEINE FOR THE TREATMENT OF ACUTE RESPIRATORY INFECTIONS IN CHILDREN

Authors

 

Aleksandra Bajec-Opančina1, Vladan Šubarević1, Katarina Stanković1, Mladen Novković1, Anita Agić2, Vladan Đorđević3,4

1Institut za majku i dete „Dr Vukan Čupić“ Beograd, Srbija /
Institute For Mother and Child „Dr. Vukan Čupić“, Belgrade, Serbia
2Abela Pharm, Beograd, Srbija / Abela Pharm, Belgrade, Serbia
3Klinika za psihijatrijske bolesti „Dr Laza Lazarević” Beograd, Srbija /
Clinic for Psychiatric Disorders „Dr. Laza Lazarević“, Belgrade, Serbia
4Farmaceutsko zdravstveni fakultet, Univerzitet u Travniku, Bosna i Hercegovina
/ Faculty of Pharmacy and Health, University of Travnik, Bosnia and Herzegovina

 


Rad je primljen 01.07.2017. / Prihvaćen 04.07.2017

 


Correspondence to


Dr. Vladan Đorđević, PhD,
Clinic for Psychiatric Disorders
„Dr. Laza Lazarević” Belgrade, Serbia
Faculty of Pharmacy and Health, University of Travnik,
Bosnia and Herzegovina
e-mail: drvladandjordjevic@gmail.com

 

 

Abstract

 

Acute respiratory infections are a very frequent problem in children, especially young ones. In case of the infections of viral origin, the symptomatology is unspecific; therefore, the therapy is symptomatic. Phytotherapy is the comparison of the pharmacological properties of chemical medicines in interaction with herbs and natural products. The modern era brought modern guidelines for herbs testing, which was confirmed by our predecessors’ experience in using herbs for healing and relieving complaints. The aim of this study was to assess the efficiency of propolis and N-acetylcisteine (PropoMucil® syrup and PropoMucil® nasal spray) in children with respiratory infections. The study was conducted during the period January-April 2016 at the Institute for Mother and Child „Dr. Vukan Čupić“ in Belgrade. The study included two groups of children: group A - children with the symptoms of the secretory inflammation of the middle ear and group B - children with the symptoms of the inflamed nasal mucosa. Demographic data and duration of symptoms were recorded for both groups at first examination, while group A was assessed for type of symptoms, otoscopic and tympanometric findings and group B was assessed for endoscopic finding, appearance and microbiological finding of the excretion both at visit one and at the follow-up visit. At follow-up, the children in group A had statistically less infection symptoms, with the normalization of the otoscopic and tympanometric findings. At the repeated examination, the children in group B had statically less infection symptoms, with the normalization of the endoscopic finding, appearance of excretion and microbiological finding.

 

 

 

Key words:

acute respiratory infections, children, propolis, N-acetylcisteine.

 

 

Sažetak

 

Akutne respiratorne infekcije su vrlo čest problem sa kojima se susreću deca, naročito mlađeg uzrasta. Simptomatologija je u slučaju virusnog porekla infekcije nespecifična, pa se je i terapija simptomatska. Fitoterapija predstavlja upoređivanje farmakoloških svojstava hemijskih lekova u interakciji sa biljem i proizvodima iz prirode. Savremeno doba donelo je moderne smernice u ispitivanjima biljaka, što je potvrdilo iskustvo naših predaka u korišćenju bilja pri lečenju i ublažavanju tegoba. Cilj istraživanja bio je da se proceni efikasnost primene propolisa i N-acetilcisteina (PropoMucil® sirupa i PropoMucil® spreja za nos) kod dece sa respiratornim infekcijama. Istraživanje je sprovedeno od januara do aprila 2016. godine u Institutu za majku i dete „Dr Vukan Čupić“ u Beogradu. Istraživanjem su obuhvaćene dve grupe dece: grupa A-deca sa simptomima sekretornog zapaljenja srednjeg uha i gupa B-deca sa simptomima zapaljenja nosne sluznice. U obe grupe dece beleženi su na prvom pregledu demografski podaci, dužina trajanja simptoma, dok su na prvom i kontrolnom pregledu beleženi tipovi simptoma, otoskopski i timpanometrijski nalaz - u grupi A i endoskopski nalaz, izgled sekreta i mikrobiološki nalaz u grupi B. U grupi A dece je pri kontrolnom pregledu statistički bila manje zastupljena simptomatologija infekcije, uz normalizaciju otoskopskog i timpanometrijskog nalaza. U grupi B dece je na ponovnom pregledu statistički bila manje zastupljena simptomatologija infekcije, došlo je do normalizacije endoskopskog nalaza, izgleda sekreta i mikrobiološkog nalaza.

 

 

Ključne reči:

akutne respiratorne infekcije, deca, propolis, N-acetilcistein.

 

 

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UDK: 615.324:638.135
615.23-053.2
616.21/.24-002-085-053.2
COBISS.SR-ID 245414412



PDF Bajec-Opančina A. et al • MD-Medical Data 2017;9(3): 149-153

 

 

 

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