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Milan Knezevic1, Gordana Andjelic2, Slobodan Loncarevic3 and Milena Knezevic4
1 Faculty of Medicine and Public Health Sciences ULPGC, Hospital Universitario Insular, Las Palmas, Spain,
2 Instiitute for Medical Research, Military Medical Academy, Belgrade, Serbia,
3 Clinic for Maxillofacial Surgery, Military Medical Academy, Belgrade, Serbia,
4 Milena Knezevic BS, Faculty of Medicine and Public Health Sciences ULPGC, Las Palmas Spain


• The paper was received on 01.03.2016. Accepted 09.03.2016.





Benign symmetric lipomatosis (BSL), or Madelung's disease is a rare of local fat distribution and it is rarely reported in the literature. The Madelung disease is presented as a symmetrical deposition of adipose tissue over the head, neck, upper part of the trunk, and proximal part of the upper extremities.The lower part of the body , the trunk and the legs are rarely afected almost not seen. It predominantly affects men between the ages of 30 and 60 years,  with a history of alcohol abuse. The disorder can also be associated with hyperlipoproteinemia, hyperuricemia, diabetes mellitus and hypothyroidism. The only effective treatment is surgical removal. A case of bilateral symmetric lipomatosis type I is described, affecting the upper neck region, bilaterally.



Key words

Benign Symmetric Lipomatosis, Morbus Madelung, Surgery





  1. Meyer TN, Meyer GPN. Caso atípico de lipomatose simétrica múltipla. Rev Soc Bras Cir Plast. 2007;22:64-6.
  2. Vieira MV, Grazziotin RU, Abreu M, Furtado CD, Silveira MF, Furtado APA, et al. Lipomatose simétrica múltipla (doença de Madelung) - Relato de um caso. Radiol Bras. 2001;34:119-21.
  3. Barbosa CC, Pires MTF, Guimarães MBS, Figueira RC, Nacif MS, Lupi O. Lipomatose simétrica benigna: doença de Madelung. Relato de caso. Rev Bras Clin Med. 2010;8:165-9.
  4. Busetto L, Sträter D, Enzi G, Coin A, Sergi G, Inelmen EM, et al. Differential clinical expression of multiple symmetric lipomatosis in men and women. Int J Obes Relat Metab Disord. 2003;27:1419-22.
  5. Lin F, Yang T. Madelung disease. CMAJ. [serial online]. 2012, Jun 25. Available from:
  6. Ramos GHA, Trevizan GL, Pepe ES. Doença de Madelung. Rev Bras Otorrinolaringol. 2002;68:587-90.

PDF Knezevic M. et al. • MD-Medical Data 2016;8(1)

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