md-medicaldata

Authors

Bojan Labus¹, Milica Pantić^1,2, Andrija Kostić^2,4, Jelena Golubović⁵, Miroslav Mišović^6,7, Nemanja Rančić<sup>6,7,8

1</sup>Clinic for Orthopedic Surgery and Traumatology, Military Medical Academy, Belgrade, Serbia
²Faculty of Medical Sciences University of Kragujevac, Kragujevac, Serbia
³Clinic of Psychiatry, University Clinical Centre Kragujevac, Kragujevac, Serbia
⁴Clinic of Neurology, KBC „Dr Dragiša Mišović-Dedinje“, Belgrade, Serbia
⁵Department of Radiology, KBC Bežanijska Kosa, Belgrade, Serbia
⁶Institute of Radiology, Military Medical Academy, Belgrade, Serbia
⁷Faculty of Medicine of the Military Medical Academy, University of Defense, Belgrade, Serbia
⁸Centre for Clinical Pharmacology, Military Medical Academy, Belgrade, Serbia

 

UDK: 616.711-006.6-07

The paper was received / Rad primljen 27.03.2025.

Accepted / Rad prihvaćen: 21.04.2025.

 

Correspondence to:

Nemanja Rančić
Vojnomedicinska akademija Beograd
Tel: 063-8524443
e-mail: nece84@hotmail.com

 

 

Abstract

 

 

Introduction: Intravascular papillary endothelial hyperplasia (IPEH) represents a rare reactive proliferation of endothelial cells around an organized thrombus, localized in a dilated blood vessel, hematoma, or vascular lesion. The symptoms that arise as a result of this lesion depend on the localization of the pathological process itself. Localization of this lesion in the spinal canal is extremely rare, so until now there are only a few published clinical cases. The aim of this work is to present the radiological diagnostic criteria of this localization. Material and method: A systematic search of the PubMed, Medline, Radiopedia databases was performed. Results: Magnetic resonance imaging shows an iso- to slightly hypointense signal on the T1, a hyperintense signal on the T2, and inhomogeneous postcontrast amplification on the T1 C+ sequence. Conclusion: Neurological symptoms are often the result of other, primarily somatic, diseases and pathological processess of different localisations. On magnetic resonance the main characteristics of IPEH are isointense to hypointense appearance on T1 and heterogeneous hyperintense appearance on T2 weighted magnetic resonance images, and also shows amplification after intravenous administration of gadolinium. It is very important to keep in mind that intravascular papillary endothelial hyperplasia often resembles a secondary deposit which can confuse radiologists. The importance of this article is in the domain of timely and adequate diagnosis and differential diagnosis, because the initially presented symptoms can resemble numerous neurological or systemic diseases.

 

Keywords:

Masson tumor, radiological diagnosis, criteria, neurology

 

 

 

Sažetak:

 

Uvod: Intravaskularna papilarna endotelna hiperplazija predstavlja retku reaktivnu proliferaciju endotelnih ćelija oko organizovanog tromba, lokalizovana u proširenom krvnom sudu, hematomu ili vaskularnoj leziji. Simptomi koji nastaju kao rezultat ove lezije zavise od lokalizacije samog patološkog procesa. Lokalizacija u kičmenom kanalu je izuzetno retka, pa je do sada objavljeno nekoliko kliničkih slučajeva. Cilj ovog rada je predstavljanje radiološko-dijagnostičkih kriterijuma ove lokalizacije. Materijal i metode: Izvršeno je sistematsko pretraživanje baza podataka PubMed, Medline, Radiopedia. Rezultati: Magnetna rezonanca pokazuje izointenzan do blago hipointenzan signal na T1 sekvenci, hiperintenzan signal na T2 sekvenci i nehomogeno postkontrastno prebojavanje na T1 C+ sekvenci. Zaključak: Neurološki simptomi su često posledica drugih, pre svega somatskih, bolesti i patoloških procesa različite lokalizacije. Na magnetnoj rezonanciji glavne karakteristike intravaskularne papilarne endotelne hiperplazije su izointenzna do hipointenzna pojava na T1 i hiperintenzna pojava na T2 ponderisanim slikama magnetne rezonance, a takođe pokazuje poboljšanje nakon intravenske primene gadolinijuma. Veoma je važno imati na umu da intravaskularna papilarna endotelna hiperplazija često podseća na sekundarni depozit koji može zbuniti radiologe i druge kliničare. Značaj ovog članka je u domenu pravovremene i adekvatne dijagnoze i diferencijalne dijagnoze, jer prvobitno ispoljeni simptomi mogu ličiti na brojne neurološke ili sistemske bolesti.

 

Ključne reči:

Massonov tumor, radiološka dijagnoza, kriterijumi, neurologija

 

 

 

 

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PDF: 003-Labus B. et al MD-Medical Data 2025;17(2) 103-106.pdf