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SVINJE KAO POTENCIJALNI ZOONOTSKI REZERVOAR BLASTOCYSTIS SP. /

PIGS AS A POTENTIAL ZOONOTIC RESERVOIR OF BLASTOCYSTIS SP.

Authors

 

Tamás Süli1,2, Gordana Kozoderović3, Vuk Vračar1 i Vesna Lalošević1

1Poljoprivredni fakultet Univerziteta u Novom Sadu
2Prophyl Animal Health Ltd, Mohács, Hungary
3Pedagoški fakultet Sombor Univerziteta u Novom Sadu

 

UDK: 616.45-089-06(497.11)"2012/2016"


The paper was received / Rad primljen: 01.06.2020.

Accepted / Rad prihvaćen: 21.06.2020.

 


Correspondence to:


Vesna Lalošević
Poljoprivredni fakultet
Departman veterinarske medicine
Trg Dositeja Obradovića 8
Novi Sad
064/2035777
e-mail: lvesna@polj.uns.ac.rs

 

 

Sažetak

 

Blastocystis  sp. je anaerobna protozoa koja kolonizuje digestivni trakt ljudi i brojnih životinja uključujući sisare i ptice. Kod inficiranih životinja nema kliničkih simptoma bolesti dok se kod ljudi povezuje sa pojavom intestinalnih tegoba i simptoma dijareje ili čak inflamatorne bolesti creva (IBD), ali do danas ne postoji konsenzus o patogenom značaju ovog parazita, jer se sreće i kod zdravih osoba. Genetska raznolikost pokazuje prisustvo više od 17 suptipova (ST) kod sisara i ptica, različite geografske distribucije, a smatra se da specifičnost za vrstu domaćina i patogenost izolata koreliraju sa varijacijama SSU-rRNA gena. Kod  ljudi se najčešće sreću ST1-ST9, sa dominacijom antropofilnog ST3, koji je nađen i kod svinja i goveda. STs 5-8 se retko sreću kod ljudi, ST 5 viđa se kod goveda i ptica, ST6 i ST7 uglavnom kod ptica. Pretpostavlja se da humane infekcije mogu biti rezultat zoonotske transmisije. U prilog tome ide činjenica visokog prisustva ovog parazita kod osoba u kontaktu sa  životinjama. ST1, ST2, ST3 i ST4 najzastupljeniji su u Evropi. ST1, ST2 i ST3 jednako su prisutni kod pacijenata sa dijarejom i kod zdravih individua, dok se  ST4 povezuje sa dijarejom i/ili IBD. Dijagnostika ovog parazita uglavnom se do sada zasnivala na mikroskopskom koprološkom pregledu, međutim molekularne metode (PCR) pokazuju daleko veću osetljivost i specifičnost, zbog čega je neophodno uvesti ih u laboratorijski rad. Razvoj odgovarajućeg protokola neophodan je za molekularnu epidemiologiju, a pomoći će u rasvetljavanju izvora Blastocystis  sp. za ljude kao i identifikaciji potencijalnih animalnih rezervoara.

                          

 

 

 

Ključne reči:

Blastocystis, svinje, ljudi, zoonoza.

 

 

Abstract

 

Blastocystis sp. is an anaerobic protozoa that colonize the digestive tract of humans and numerous animals such as mammals and birds. In infected animals there are no clinical symptoms of the disease while in humans it is associated with the appearance of intestinal problems and diarrheal symptoms or even inflammatory bowel disease (IBD), although there is no consensus on the pathogenic significance of this parasite because it is found in healthy persons as well. Genetic diversity shows the presence of 17 subtypes (ST) with different geographical distribution in mammals and birds, and it is considered that host specificity and pathogenicity of isolates are in corrleation with variations in SSU-rRNA gene. In humans ST1-ST9 are most likely to be found, with domination of the anthropophilic ST3, which found in pigs and cattle, respectively. STs 5-8 are rarely found in humans, while ST 5 is found in cattle and birds, and ST6 and ST7 mainly in birds. It is assumed that human infections may be the result of zoonotic transmission. In favor of this is the fact of the high prevalence of this parasite in those people who are in contact with animals. ST1, ST2, ST3 and ST4 are the most prevalent in Europe. ST1, ST2, and ST3 are equally present in patients with diarrhea and in healthy indivduals, while ST4 is associated with diarrhea and / or IBS. Diagnostics of this parasite has mainly been based on microscopic coprological exam, but molecular methods (PCR) show far greater sensitivity and specificity, which is why it is necessary to introduce them into laboratory work. Development of the appropriate protocols is necessary for molecular epidemiology and it will help to identify the source of Blastocystis sp. for humans, as well as potential animal reservoirs.

 

 

Key words:

Blastocystis, pigs, humans, zoonose.

 

 

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PDF Süli T. et al • MD-Medical Data 2020;12(2): 107-112

 

 

 

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